API Palmitoylethanolamide(PEA) pain relief benefits, reviews CAS 544-31-0

1. Palmitoylethanolamide (544-31-0) Description


Palmitoylethanolamide (PEA) is an endogenous fatty acid amide, belonging to the class of nuclear factor agonists. PEA has been demonstrated to bind to a receptor in the cell-nucleus (a nuclear receptor) and exerts a great variety of biological functions related to chronic pain and inflammation. The main target is thought to be the peroxisome proliferator-activated receptor alpha (PPAR-α). However, the presence of PEA (and other structurally related N-acylethanolamines) has been known to enhance anandamide activity by a so-called "entourage effect".  Palmitoylethanolamide/PEA has been shown to have anti-inflammatory, anti-nociceptive, neuroprotective, and anticonvulsant properties.

2. Palmitoylethanolamide (544-31-0) Specifications

Product Name
Palmitoylethanolamide
Chemical Name
Palmitoylethanolamide;
(2-Hydroxyethyl)hexadecanamide;
Hydroxyethylpalmitamide;
Palmidrol;
N-Palmitoylethanolamine;
Brand Name
No data for available
Drug Class
Amines, Pharmaceuticals, Intermediates & Fine Chemicals
CAS Number
544-31-0
InChIKey
HXYVTAGFYLMHSO-UHFFFAOYSA-N
Molecular Formula
C18H37NO2
Molecular Weight
299.499 g/mol
Monoisotopic Mass
299.50 g /mol
Melting Point 
93 to 98 °C (199 to 208 °F; 366 to 371 K)
Boiling point
461.5 °C at 760 mmHg
Biological Half-Life
No Data Available
Color
White to Off-White Solid
Solubility 
Chloroform (Sparingly), Methanol (Sparingly)
Storage Temperature 
−20°C
Palmitoylethanolamide Application
Palmitoylethanolamide is an endogenous CB2 cannabinoid receptor agonist and selective GPR55 agonist.


3. Palmitoylethanolamide (544-31-0) video

https://vimeo.com/309416710

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